The ingredients in FOCUS are natural ingredients and the shelf life is one year. However, the appearance of the product might change as this is NOT a synthetic product. CBD tends to change color and we do recommend to optimize the nano-sonification to use in a timely manner. Refrigerating the product may extend the shelf life of the unopened product and should always be stored in a cool, dry environment. Upon opening, we recommend using it within 60 days for optimal benefits.